People are often concerned about whether fatigue or sleep deprivation can mimic signs of intoxication, and yes, they absolutely can.
There are many scientific studies on this, especially involving 18-wheeler drivers, since fatigue-related impairment is studied so often in that context.
Police officers are trained on this issue as well.
They do not always take it into consideration, but it is definitely something that can matter in a DWI investigation.
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